Location:
United States
Description:
This audiobook is narrated by a digital voice. In the era of big data and personalized medicine, Applications of Multi-Omics serves as a comprehensive guide to integrating biological data across genomics, transcriptomics, proteomics, metabolomics, and epigenomics. This book explores how multi-omics technologies provide a holistic view of biological systems, transforming our understanding of human health, disease mechanisms, drug development, and environmental science. Written for researchers, healthcare professionals, and students in life sciences, this book breaks down complex concepts into accessible insights, covering key methodologies, computational approaches, and real-world applications. From precision medicine and biomarker discovery to AI-driven data integration and ethical considerations, Applications of Multi-Omics provides a deep dive into how multi-layered biological data is revolutionizing biomedical research and healthcare. Whether you are an academic researcher seeking to integrate multi-omics in your studies, a clinician exploring omics-driven diagnostics, or a data scientist working at the intersection of AI and life sciences, this book is an essential resource. It highlights emerging trends, challenges, and future directions in multi-omics, paving the way for groundbreaking discoveries in personalized medicine, biotechnology, and agricultural research. Join the multi-omics revolution and uncover the intricate biological networks shaping the future of science and medicine. Duration - 17h 33m. Author - Richard Skiba. Narrator - Digital Voice Cole G. Published Date - Monday, 20 January 2025. Copyright - © 2025 Richard Skiba ©.
Language:
English
Preface
Duration:00:03:35
Chapter 1: Introduction to Multi-Omics
Duration:00:01:56
Definition and Scope of Multi-Omics
Duration:02:08:44
Historical Development of Omics Technologies
Duration:00:25:04
Importance
Duration:00:07:39
Overview of Key Challenges and Opportunities
Duration:00:05:01
Chapter 2: Fundamentals of Genomics
Duration:00:01:53
Structure and Function of the Genome
Duration:00:27:48
DNA Sequencing Technologies (Next-Generation Sequencing, Third-Generation Sequencing)
Duration:00:38:55
Applications of Genomics in Disease Research and Personalised Medicine
Duration:00:51:37
Challenges In Genomic Data Analysis
Duration:00:08:07
Chapter 3: Understanding Transcriptomics
Duration:00:01:51
RNA Biology and Gene Expression
Duration:00:14:06
RNA Sequencing (RNA-Seq) and Microarrays
Duration:00:07:27
Applications in Cancer, Neuroscience, and Infectious Diseases
Duration:00:07:57
Computational Tools for Transcriptomics
Duration:00:08:56
Chapter 4: The Role of Proteomics in Biology
Duration:00:01:57
Protein Structure and Function
Duration:00:16:01
Mass Spectrometry and Protein Identification
Duration:00:24:22
Proteomics in Biomarker Discovery and Drug Development
Duration:00:05:56
Challenges in Proteomic Data Interpretation
Duration:00:31:40
Chapter 5: Metabolomics and Its Biological Significance
Duration:00:02:18
The Metabolome and Metabolic Pathways
Duration:00:25:27
Techniques for Metabolomics (NMR, LC-MS, GC-MS)
Duration:00:27:48
Metabolomics in Disease Diagnosis and Environmental Studies
Duration:00:27:54
Integration of Metabolomic Data with Other Omics
Duration:00:03:23
Chapter 6: Epigenomics and Gene Regulation
Duration:00:02:17
DNA Methylation, Histone Modification, and Chromatin Remodelling
Duration:00:35:35
Techniques for Studying Epigenetics (ChIP-Seq, ATAC-Seq, Bisulphite Sequencing)
Duration:00:12:59
Epigenomics in Aging, Cancer, and Mental Health Disorders
Duration:00:16:43
Role of Epigenetics in Precision Medicine
Duration:00:30:55
Chapter 7: Integrative Multi-Omics Approaches
Duration:00:02:36
Data Integration Strategies for Multi-Omics Research
Duration:01:41:13
Bioinformatics Pipelines and AI-Driven Analytics
Duration:00:10:21
Network Biology and Pathway Analysis
Duration:00:24:17
Case Studies of Successful Multi-omics Integration
Duration:00:07:18
Chapter 8: Multi-Omics in Personalized Medicine
Duration:00:02:06
The Promise of Precision Medicine
Duration:00:39:09
Pharmacogenomics and Drug Response Predictions
Duration:00:42:56
Multi-omics in Rare Diseases and Individualized Therapies
Duration:00:15:35
Ethical and Regulatory Considerations in Personalized Medicine
Duration:00:08:45
Chapter 9: Multi-Omics in Disease Research
Duration:00:02:06
Cancer: Genomics, Transcriptomics, and Proteomics in Tumour Biology
Duration:00:38:55
Neurodegenerative Diseases: Multi-omics Insights into Alzheimer's and Parkinson's
Duration:00:06:35
Autoimmune Diseases: Integrative Approaches in Immunology
Duration:00:07:14
Infectious Diseases: Understanding Host-Pathogen Interactions
Duration:00:07:11
Chapter 10: Multi-Omics in Agriculture and Environmental Science
Duration:00:02:14
Crop Improvement Using Genomics and Metabolomics
Duration:00:33:48
Soil Microbiome and Its Impact on Agriculture
Duration:00:06:12
Climate Change and Its Effects on the Metabolome
Duration:00:05:59
Applications in Food Safety and Nutritional Science
Duration:00:10:42
Chapter 11: Big Data, AI, and Machine Learning in Multi-Omics
Duration:00:02:02
Role of AI and Machine Learning in Omics Analysis
Duration:00:27:06
Data Storage, Processing, and Cloud-based Bioinformatics Tools
Duration:00:08:32
Overcoming Data Integration Challenges
Duration:00:04:20
The future of AI in Multi-omics Research
Duration:00:04:23
Chapter 12: Ethical, Legal, and Social Implications of Multi-Omics
Duration:00:02:10
Data Privacy and Security in Multi-omics Research
Duration:00:08:23
Ethical Challenges in Human Genetic Studies
Duration:00:06:19
Regulations and Policies in Multi-omics-Driven Healthcare
Duration:00:03:57
Public Perception and Engagement in Omics Research
Duration:00:05:10