NBC Nightly News with Lester Holt

American Airlines temporarily grounds all flights, snarling holiday travel; Starbucks union strike expands as workers demand pay raises; Bird flu reaches zoos, further threatening endangered species; and more on tonight’s broadcast.

New report says Matt Gaetz may have violated laws on prostitution, statutory rape; Holiday travel ramps up as holiday week begins; Luigi Mangione pleads not guilty to New York state charges in UnitedHealthcare CEO murder; and more on tonight’s broadcast.

Amtrak delays snarl holiday train travel along much of East Coast; Man shot, killed by police after driving into Texas mall during high-speed chase; U.S. fighter jet shot down by friendly fire over Red Sea; and more on tonight’s broadcast.

At least 5 killed, 200 injured after car plows into Christmas market in Germany; Biden signs funding bill after Congress narrowly avoids government shutdown; Winter weather hits coast to coast, threatening holiday travel; and more on tonight’s broadcast

Car rams into crowd at German Christmas market, killing at least two, injuring dozens; House approves stopgap spending bill, hours before shutdown deadline; Richard Allen, convicted of Delphi murders, sentenced to 130 years in prison; and more on tonight’s broadcast.

Suspect in CEO killing extradited from Pennsylvania to New York; Congress scrambles to save spending plan to avoid government shutdown; Shooter in Wisconsin communicated with California man before shooting, according to court documents; and more on tonight’s broadcast.

Trump denounces massive spending bill, pushing government closer to shutdown; CDC reports first severe case of bird flu in U.S.; Stocks drop sharply after Fed cuts interest rates and signals more cautious approach next year; and more on tonight’s broadcast.

Three dead, six injured in Wisconsin elementary school mass shooting, police said; Much of Northeast remains on edge over reported drone sightings; Indictment of suspect in CEO shooting could come any day; and more on tonight’s broadcast.

Growing calls for action as drone sightings increase; Rare tornado hits Northern California; A grand jury indictment could come this week in the CEO murder case; and more on tonight’s broadcast.

On the hunt for mystery drones; CEO murder suspect gets a new, high-profile lawyer; President-elect Trump attends Army-Navy game with political allies; and more on tonight’s broadcast.

Before captivating audiences as “Elphaba” in the hit Broadway musical Wicked, Jessica Vosk was crunching numbers on Wall Street. But after being plagued by panic attacks, the actress and singer decided to take a leap of faith, and pursue her life-long dream of performing. In a candid conversation with NBC News’ Kate Snow, Vosk reflects on the risks she took, her latest Broadway production, the American Idol audition that nearly ended her dream before it began.

Wave of new mystery drone sightings in several states as officials call for answers; New details of how authorities found CEO murder suspect; Fellow prisoner reported seeing American Austin Tice in Syria; and more on tonight’s broadcast.

Suspect in CEO killing fights extradition to New York; New round of heavy lake effect snow hits Upper Midwest and Northeast; Lawmakers demand answers about mystery drone sightings over several states; and more on tonight’s broadcast.

FBI director Wray says he'll resign before Trump inauguration; Police say gun in CEO killing matches casings found at crime scene; Progress in Southern California wildfire battle, but threat continues; and more on tonight’s broadcast.

Suspect in insurance CEO killing will fight extradition from Pennsylvania to New York; new details about Luigi Mangione, suspect in healthcare CEO killing; fire blows up in Southern California, destroying homes and forcing thousands to evacuate; and more on tonight’s broadcast.

'Strong person of interest' arrested in killing of UnitedHealthcare CEO; After Assad is driven out of Syria, celebrations and searches for the missing; Daniel Penny acquitted in subway chokehold death; and more on tonight’s broadcast.

Rebels take control of Syria, Assad flees country; New photos of a person of interest in CEO murder as manhunt widens; President-elect Trump speaks exclusively with NBC News’ Kristen Welker; and more on tonight’s broadcast.

New details emerge in the manhunt for insurance CEO's killer; Notre Dame Cathedral reopens in Paris five years after fire; Kristen Welker's exclusive interview with President-elect Donald Trump; and more on tonight’s broadcast.

Manhunt for suspected shooter of UnitedHealthcare CEO in third day; Judge drops most serious charge against suspect in subway chokehold death; After a week of snow, yet more for the Great Lakes region; and more on tonight’s broadcast.

As the manhunt continues, new images released of a person of interest in the killing of UnitedHealthcare CEO; Earthquake rattles coast of California and triggers brief tsunami warning; More heavy snow and high winds in Great Lakes and Midwest; and more on tonight’s broadcast.